Functional and Structural Similarities between the Internal Ribosome Entry Sites of Hepatitis C Virus and Porcine Teschovirus, a Picornavirus

Initiation of protein synthesis on picornavirus RNA requires an internal ribosome entry site (IRES). Typically, picornavirus IRES elements contain about 450 nucleotides (nt) and use most of the cellular translation initiation factors. However, it is now shown that just 280 nt of the porcine teschovi...

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Main Authors: Pisarev, Andrey V., Chard, Louisa S., Kaku, Yoshihiro, Johns, Helen L., Shatsky, Ivan N., Belsham, Graham J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC387690/
https://ncbi.nlm.nih.gov/pubmed/15078929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4487-4497.2004
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