Sox9b Is Required for Epicardium Formation and Plays a Role in TCDD-Induced Heart Malformation in Zebrafish

Activation of the transcription factor aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) prevents the formation of the epicardium and leads to severe heart malformations in developing zebrafish (Danio rerio). The downstream genes that cause heart malformation are not known. Bec...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hofsteen, Peter, Plavicki, Jessica, Johnson, Shaina D., Peterson, Richard E., Heideman, Warren
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2013
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876814/
https://ncbi.nlm.nih.gov/pubmed/23775563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.086413
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker