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Catalytic, Enantioselective 1,3-Dipolar Cycloadditions of Nitrile Imines with Methyleneindolinones

Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones are reported. The spiro[pyrazolin[3,3′-oxindole] products are formed in good yields (up to 98%) and high enantioselectivity (up to 99% ee).

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Detalhes bibliográficos
Main Authors: Gerten, Anthony L., Slade, Michael C., Pugh, Kelsie M., Stanley, Levi M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876797/
https://ncbi.nlm.nih.gov/pubmed/24132663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob41815d
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