Hepatic Cytochrome P450s, Phase II Enzymes and Nuclear Receptors Are Downregulated in a Th2 Environment during Schistosoma mansoni Infection

Inflammation and infection downregulate the activity and expression of cytochrome P450s (P450s) and other drug metabolizing enzymes (DMEs) involved in hepatic drug clearance. Schistosoma mansoni infection was reported to cause a downregulation of hepatic P450-dependent activities in mouse liver, but...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mimche, Sylvie M., Nyagode, Beatrice A., Merrell, Matthew D., Lee, Choon-Myung, Prasanphanich, Nina S., Cummings, Richard D., Morgan, Edward T.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876789/
https://ncbi.nlm.nih.gov/pubmed/24163175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.113.054957
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados