In Vitro Replication of Hepatitis E Virus (HEV) Genomes and of an HEV Replicon Expressing Green Fluorescent Protein

Hepatitis E virus (HEV) RNA replication occurred in seven of nine primate cell cultures transfected with in vitro transcripts of an infectious cDNA clone. Cell-to-cell spread did not occur in cell cultures, but rhesus monkeys inoculated with lysates of HEV-transfected PLC/PRF/5 and Huh-7 cells becam...

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Main Authors: Emerson, Suzanne U., Nguyen, Hanh, Graff, Judith, Stephany, David A., Brockington, Alicia, Purcell, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC387676/
https://ncbi.nlm.nih.gov/pubmed/15078965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.9.4838-4846.2004
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