Apoptosis Induced by the Histone Deacetylase Inhibitor FR901228 in Human T-Cell Leukemia Virus Type 1-Infected T-Cell Lines and Primary Adult T-Cell Leukemia Cells

Inhibition of histone deacetylase (HDAC) activity induces growth arrest, differentiation, and, in certain cell types, apoptosis. FR901228, FK228, or depsipeptide, is an HDAC inhibitor effective in T-cell lymphomas. Adult T-cell leukemia (ATL) is caused by human T-cell leukemia virus type 1 (HTLV-1)...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Mori, Naoki, Matsuda, Takehiro, Tadano, Masayuki, Kinjo, Takao, Yamada, Yasuaki, Tsukasaki, Kunihiro, Ikeda, Shuichi, Yamasaki, Yoshihiro, Tanaka, Yuetsu, Ohta, Takao, Iwamasa, Teruo, Tomonaga, Masao, Yamamoto, Naoki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Transformation and Oncogenesis
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387669/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15078940/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.9.4582-4590.2004
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge