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pdf1, a Palmitoyl Protein Thioesterase 1 Ortholog in Schizosaccharomyces pombe: a Yeast Model of Infantile Batten Disease

Infantile Batten disease is a severe neurodegenerative storage disorder caused by mutations in the human PPT1 (palmitoyl protein thioesterase 1) gene, which encodes a lysosomal hydrolase that removes fatty acids from lipid-modified proteins. PPT1 has orthologs in many species, including lower organi...

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Detalhes bibliográficos
Main Authors: Cho, Steve K., Hofmann, Sandra L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387660/
https://ncbi.nlm.nih.gov/pubmed/15075260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.2.302-310.2004
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