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The role of a non-canonical JAK-STAT pathway in IFN therapy of poxvirus infection and multiple sclerosis: An example of Occam’s Broom?

Signaling by cytokines such as the interferons (IFNs) involves Janus kinases (JAKs) and signal transducer and activator of transcription (STAT) transcription factors. The beauty of the classical model of JAK-STAT signaling is its simplicity in that JAK-activated STATs in the nucleus are responsible...

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Detalles Bibliográficos
Main Authors: Ahmed, Chulbul M, Johnson, Howard M
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876437/
https://ncbi.nlm.nih.gov/pubmed/24416655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.26227
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