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Controlling Nuclear Jaks and Stats for Specific Gene Activation by Ifn γ and Other Cytokines: A Possible Steroid-like Connection

The mechanism of specific gene activation by cytokines that use JAK/STAT signalling pathway is unknown. There are four different types of JAKs and seven different types of STATs. In the classical model of signaling, ligand interacts solely with the receptor extracellular domain, which triggers JAK a...

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Detalhes bibliográficos
Main Authors: Johnson, Howard M., Noon-Song, Ezra, Ahmed, Chulbul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424617/
https://ncbi.nlm.nih.gov/pubmed/22924155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000112
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