The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination

Vaccines are the most effective agents to control infections. In addition to the pathogen antigens, vaccines contain adjuvants that are used to enhance protective immune responses. However, the molecular mechanism of action of most adjuvants is ill-known, and a better understanding of adjuvanticity...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vono, Maria, Taccone, Marianna, Caccin, Paola, Gallotta, Marilena, Donvito, Giovanna, Falzoni, Simonetta, Palmieri, Emiliano, Pallaoro, Michele, Rappuoli, Rino, Di Virgilio, Francesco, De Gregorio, Ennio, Montecucco, Cesare, Seubert, Anja
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876261/
https://ncbi.nlm.nih.gov/pubmed/24324152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319784110
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