The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination

Vaccines are the most effective agents to control infections. In addition to the pathogen antigens, vaccines contain adjuvants that are used to enhance protective immune responses. However, the molecular mechanism of action of most adjuvants is ill-known, and a better understanding of adjuvanticity...

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Bibliografiska uppgifter
Huvudupphovsmän: Vono, Maria, Taccone, Marianna, Caccin, Paola, Gallotta, Marilena, Donvito, Giovanna, Falzoni, Simonetta, Palmieri, Emiliano, Pallaoro, Michele, Rappuoli, Rino, Di Virgilio, Francesco, De Gregorio, Ennio, Montecucco, Cesare, Seubert, Anja
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876261/
https://ncbi.nlm.nih.gov/pubmed/24324152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319784110
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