Necking and failure of constrained 3D microtissues induced by cellular tension

In this paper we report a fundamental morphological instability of constrained 3D microtissues induced by positive chemomechanical feedback between actomyosin-driven contraction and the mechanical stresses arising from the constraints. Using a 3D model for mechanotransduction we find that perturbati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Hailong, Svoronos, Alexander A., Boudou, Thomas, Sakar, Mahmut Selman, Schell, Jacquelyn Youssef, Morgan, Jeffrey R., Chen, Christopher S., Shenoy, Vivek B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Physical Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876233/
https://ncbi.nlm.nih.gov/pubmed/24324149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313662110
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