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Necking and failure of constrained 3D microtissues induced by cellular tension
In this paper we report a fundamental morphological instability of constrained 3D microtissues induced by positive chemomechanical feedback between actomyosin-driven contraction and the mechanical stresses arising from the constraints. Using a 3D model for mechanotransduction we find that perturbati...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876233/ https://ncbi.nlm.nih.gov/pubmed/24324149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313662110 |
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