Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics

Phosphatidylinositol 3,5-bisphosphate [PI(3,5)P(2)] is a low-abundance phosphoinositide presumed to be localized to endosomes and lysosomes, where it recruits cytoplasmic peripheral proteins and regulates endolysosome-localized membrane channel activity. Cells lacking PI(3,5)P(2) exhibit lysosomal t...

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Hlavní autoři: Li, Xinran, Wang, Xiang, Zhang, Xiaoli, Zhao, Mingkun, Tsang, Wai Lok, Zhang, Yanling, Yau, Richard Gar Wai, Weisman, Lois S., Xu, Haoxing
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876232/
https://ncbi.nlm.nih.gov/pubmed/24324172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311864110
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