Cbl-b Enhances Sensitivity to 5-Fluorouracil via EGFR- and Mitochondria-Mediated Pathways in Gastric Cancer Cells

5-Fluorouracil (5-FU) is an essential component of anticancer chemotherapy against gastric cancer. However, the response rate of single drug is still limited. The ubiquitin ligase Cbl-b is a negative regulator of growth factor receptor signaling and is involved in the suppression of cancer cell prol...

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Main Authors: Feng, Dan, Ma, Yanju, Liu, Jing, Xu, Ling, Zhang, Ye, Qu, Jinglei, Liu, Yunpeng, Qu, Xiujuan
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876118/
https://ncbi.nlm.nih.gov/pubmed/24351824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms141224399
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