Cardiac Ablation of Rheb1 Induces Impaired Heart Growth, Endoplasmic Reticulum-Associated Apoptosis and Heart Failure in Infant Mice

Ras homologue enriched in brain 1 (Rheb1) plays an important role in a variety of cellular processes. In this study, we investigate the role of Rheb1 in the post-natal heart. We found that deletion of the gene responsible for production of Rheb1 from cardiomyocytes of post-natal mice resulted in mal...

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Detalhes bibliográficos
Main Authors: Cao, Yunshan, Tao, Lichan, Shen, Shutong, Xiao, Junjie, Wu, Hang, Li, Beibei, Wu, Xiangqi, Luo, Wen, Xiao, Qi, Hu, Xiaoshan, Liu, Hailang, Nie, Junwei, Lu, Shuangshuang, Yuan, Baiyin, Han, Zhonglin, Xiao, Bo, Yang, Zhongzhou, Li, Xinli
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876117/
https://ncbi.nlm.nih.gov/pubmed/24351823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms141224380
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