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Investigation of siRNA Nanoparticle Formation Using Mono-Cationic Detergents and Its Use in Gene Silencing in Human HeLa Cells

The focus of recent research has been on the development of siRNA vectors to achieve an innovative gene therapy. Most of the conventional vectors are siRNA nanoparticles complexed with cationic polymers and liposomes, making it difficult to release siRNA. In this study, we report on the use of MCD,...

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Hlavní autoři: Yamada, Yuma, Suzuki, Ryosuke, Harashima, Hideyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875945/
https://ncbi.nlm.nih.gov/pubmed/24202451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers5041413
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