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Investigation of siRNA Nanoparticle Formation Using Mono-Cationic Detergents and Its Use in Gene Silencing in Human HeLa Cells

The focus of recent research has been on the development of siRNA vectors to achieve an innovative gene therapy. Most of the conventional vectors are siRNA nanoparticles complexed with cationic polymers and liposomes, making it difficult to release siRNA. In this study, we report on the use of MCD,...

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Detalhes bibliográficos
Main Authors: Yamada, Yuma, Suzuki, Ryosuke, Harashima, Hideyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875945/
https://ncbi.nlm.nih.gov/pubmed/24202451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers5041413
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