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Integrative transcriptome sequencing identifies trans-splicing events with important roles in human embryonic stem cell pluripotency

Trans-splicing is a post-transcriptional event that joins exons from separate pre-mRNAs. Detection of trans-splicing is usually severely hampered by experimental artifacts and genetic rearrangements. Here, we develop a new computational pipeline, TSscan, which integrates different types of high-thro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Chan-Shuo, Yu, Chun-Ying, Chuang, Ching-Yu, Hsiao, Michael, Kao, Cheng-Fu, Kuo, Hung-Chih, Chuang, Trees-Juen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875859/
https://ncbi.nlm.nih.gov/pubmed/24131564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.159483.113
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