NCLscan: accurate identification of non-co-linear transcripts (fusion, trans-splicing and circular RNA) with a good balance between sensitivity and precision

Analysis of RNA-seq data often detects numerous ‘non-co-linear’ (NCL) transcripts, which comprised sequence segments that are topologically inconsistent with their corresponding DNA sequences in the reference genome. However, detection of NCL transcripts involves two major challenges: removal of fal...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Chuang, Trees-Juen, Wu, Chan-Shuo, Chen, Chia-Ying, Hung, Li-Yuan, Chiang, Tai-Wei, Yang, Min-Yu
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756807/
https://ncbi.nlm.nih.gov/pubmed/26442529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1013
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