Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair

Sequence-specific nucleases like TALENs and the CRISPR/Cas9 system have greatly expanded the genome editing possibilities in model organisms such as zebrafish. Both systems have recently been used to create knock-out alleles with great efficiency, and TALENs have also been successfully employed in k...

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Bibliografiske detaljer
Main Authors: Auer, Thomas O., Duroure, Karine, De Cian, Anne, Concordet, Jean-Paul, Del Bene, Filippo
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2014
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875856/
https://ncbi.nlm.nih.gov/pubmed/24179142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.161638.113
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