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Deep Gray Matter Demyelination Detected by Magnetization Transfer Ratio in the Cuprizone Model

In multiple sclerosis (MS), the correlation between lesion load on conventional magnetic resonance imaging (MRI) and clinical disability is weak. This clinico-radiological paradox might partly be due to the low sensitivity of conventional MRI to detect gray matter demyelination. Magnetization transf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fjær, Sveinung, Bø, Lars, Lundervold, Arvid, Myhr, Kjell-Morten, Pavlin, Tina, Torkildsen, Øivind, Wergeland, Stig
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875491/
https://ncbi.nlm.nih.gov/pubmed/24386344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084162
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