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Omalizumab may decrease IgE synthesis by targeting membrane IgE+ human B cells
BACKGROUND: Omalizumab, is a humanized anti-IgE monoclonal antibody used to treat allergic asthma. Decreased serum IgE levels, lower eosinophil and B cell counts have been noted as a result of treatment. In vitro studies and animal models support the hypothesis that omalizumab inhibits IgE synthesis...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3875359/ https://ncbi.nlm.nih.gov/pubmed/24004581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-7022-3-29 |
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