Omalizumab decreases IgE production in patients with allergic (IgE-mediated) asthma; PKPD analysis of a biomarker, total IgE

AIM: To determine whether excessive IgE production by patients with atopic allergic asthma decreases with omalizumab therapy. METHODS: Omalizumab, free and total IgE data were obtained from an epidemiological study and six randomized, double-blind, placebo-controlled trials in patients with allergic...

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Bibliographic Details
Main Authors: Lowe, Philip J, Renard, Didier
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2011
Subjects:
Uropharmacology Themed Section
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162660/
https://ncbi.nlm.nih.gov/pubmed/21392073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.03962.x
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