Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells

The nature of the antigens recognized by γδ T cells and their potential recognition of major histocompatibility complex (MHC)-like molecules has remained unclear. The CD1 family of lipid-presenting molecules are suggested ligands for Vδ1 TCR-expressing γδ T cells, the major γδ lymphocyte population...

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Main Authors: Luoma, Adrienne M., Castro, Caitlin D., Mayassi, Toufic, Bembinster, Leslie A., Bai, Li, Picard, Damien, Anderson, Brian, Scharf, Louise, Kung, Jennifer E., Sibener, Leah V., Savage, Paul B., Jabri, Bana, Bendelac, Albert, Adams, Erin J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875342/
https://ncbi.nlm.nih.gov/pubmed/24239091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.11.001
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