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Congenital brain serotonin deficiency leads to reduced ethanol sensitivity and increased ethanol consumption in mice

Serotonergic dysfunction has been hypothesized to play an important role in the pathophysiology of alcoholism. However, whether congenital serotonin (5-HT) deficiency leads to increased alcohol consumption or affects ethanol-related behaviors has not been established. Here, we use a transgenic mouse...

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Bibliographic Details
Main Authors: Sachs, Benjamin D., Salahi, A. Ayten, Caron, Marc G.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874885/
https://ncbi.nlm.nih.gov/pubmed/24067926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.09.010
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