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Cortical–Amygdalar Circuit Dysfunction in a Genetic Mouse Model of Serotonin Deficiency

Although the majority of first-line antidepressants increase brain serotonin and rare polymorphisms in tryptophan hydroxlase-2 (Tph2), the rate-limiting enzyme in the brain serotonin synthesis pathway, have been identified in cohorts of subjects with major depressive disorder, the circuit level alte...

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Autors principals: Dzirasa, Kafui, Kumar, Sunil, Sachs, Benjamin D., Caron, Marc G., Nicolelis, Miguel A. L.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633471/
https://ncbi.nlm.nih.gov/pubmed/23467366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4891-12.2013
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