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Cortical–Amygdalar Circuit Dysfunction in a Genetic Mouse Model of Serotonin Deficiency
Although the majority of first-line antidepressants increase brain serotonin and rare polymorphisms in tryptophan hydroxlase-2 (Tph2), the rate-limiting enzyme in the brain serotonin synthesis pathway, have been identified in cohorts of subjects with major depressive disorder, the circuit level alte...
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Autores principales: | , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
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Society for Neuroscience
2013
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633471/ https://ncbi.nlm.nih.gov/pubmed/23467366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4891-12.2013 |
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