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Melatonin MT(1) and MT(2) receptors display different molecular pharmacologies only in the G-protein coupled state
BACKGROUND AND PURPOSE: Melatonin receptors have been extensively characterized regarding their affinity and pharmacology, mostly using 2-[(125)I]-melatonin as a radioligand. Although [(3)H]-melatonin has the advantage of corresponding to the endogenous ligand of the receptor, its binding has not be...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Ltd
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874706/ https://ncbi.nlm.nih.gov/pubmed/24117008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12457 |
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