Recombinant Human Melatonin Receptor MT1 Isolated in Mixed Detergents Shows Pharmacology Similar to That in Mammalian Cell Membranes

The human melatonin MT1 receptor—belonging to the large family of G protein-coupled receptors (GPCRs)—plays a key role in circadian rhythm regulation and is notably involved in sleep disorders and depression. Structural and functional information at the molecular level are highly desired for fine ch...

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Bibliographic Details
Main Authors: Logez, Christel, Berger, Sylvie, Legros, Céline, Banères, Jean-Louis, Cohen, William, Delagrange, Philippe, Nosjean, Olivier, Boutin, Jean A., Ferry, Gilles, Simonin, Frédéric, Wagner, Renaud
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069108/
https://ncbi.nlm.nih.gov/pubmed/24959712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100616
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