Effects of transforming growth factor β2 and connective tissue growth factor on induction of epithelial mesenchymal transition and extracellular matrix synthesis in human lens epithelial cells

AIM: To investigate the effects of transforming growth factor β2 (TGF-β2) and connective tissue growth factor (CTGF) on transdifferentiation of human lens epithelial cells (HLECs) cultured in vitro and synthesis of extracellular matrix (ECM). METHODS: HLECs were treated with TGF-β2 (0, 0.5, 1.0, 5,...

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Autori principali: Pei, Cheng, Ma, Bo, Kang, Qian-Yan, Qin, Li, Cui, Li-Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Journal of Ophthalmology Press 2013
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874511/
https://ncbi.nlm.nih.gov/pubmed/24392320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2013.06.03
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