Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: implications for cardiac hypertrophy.

The accelerated protein accumulation characteristic of cardiomyocyte hypertrophy results from increased cellular protein synthetic capacity (elevated ribosome content). The rate limiting step in ribosome accumulation is transcription of the rRNA genes. During neonatal cardiomyocyte hypertrophy induc...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hannan, R D, Stefanovsky, V, Taylor, L, Moss, T, Rothblum, L I
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC38745/
https://ncbi.nlm.nih.gov/pubmed/8710943
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы