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Development and validation of LC-HRMS and GC-NICI-MS methods for stereoselective determination of MDMA and its phase I and II metabolites in human urine

3,4-Methylenedioxymethamphetamine (MDMA) is a racemic drug of abuse and its R- and S-enantiomers are known to differ in their dose-response curve. The S-enantiomer was shown to be eliminated at a higher rate than the R-enantiomer most likely explained by stereoselective metabolism that was observed...

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Autores principales: Schwaninger, Andrea E., Meyer, Markus R., Huestis, Marilyn A., Maurer, Hans H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874414/
https://ncbi.nlm.nih.gov/pubmed/21656610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.1929
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