Stereoselective Urinary MDMA (Ecstasy) and Metabolites Excretion Kinetics following Controlled MDMA Administration to Humans

The R- and S-enantiomers of racemic 3,4-methylenedioxymethamphetamine (MDMA) exhibit different dose-concentration curves. In plasma, S-MDMA was eliminated at a higher rate, most likely due to stereoselective metabolism. Similar data were shown in various in vitro experiments. The aim of the present...

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Detalhes bibliográficos
Main Authors: Schwaninger, Andrea E., Meyer, Markus R., Barnes, Allan J., Kolbrich-Spargo, Erin A., Gorelick, David A., Goodwin, Robert S., Huestis, Marilyn A., Maurer, Hans H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225738/
https://ncbi.nlm.nih.gov/pubmed/21983032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.09.023
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