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Stem cell quiescence acts as a tumor suppressor in squamous tumors

In some organs, adult stem cells are uniquely poised to serve as cancer cells of origin. It is unclear, however, whether tumorigenesis is influenced by the activation state of the adult stem cell. Hair follicle stem cells (HFSCs) act as cancer cells of origin for cutaneous squamous cell carcinoma (S...

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Detalhes bibliográficos
Main Authors: White, AC, Khuu, JK, Dang, CY, Hu, J, Tran, KV, Liu, A, Gomez, S, Zhang, Z, YI, R, Scumpia, P, Grigorian, M, Lowry, WE
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874399/
https://ncbi.nlm.nih.gov/pubmed/24335650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2889
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