Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing

Most unwanted RNA transcripts in the nucleus of eukaryotic cells, such as splicing-defective pre-mRNAs and spliced-out introns, are rapidly degraded by the nuclear exosome. In budding yeast, a number of these unwanted RNA transcripts, including spliced-out introns, are first recognized by the nuclea...

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Bibliographic Details
Main Authors: Kong, Ka-Yiu Edwin, Tang, Hei-Man Vincent, Pan, Kewu, Huang, Zhe, Lee, Tsz-Hang Jimmy, Hinnebusch, Alan G., Jin, Dong-Yan, Wong, Chi-Ming
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874199/
https://ncbi.nlm.nih.gov/pubmed/24097436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt888
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