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Transcription factor binding to Caenorhabditis elegans first introns reveals lack of redundancy with gene promoters

Gene expression is controlled through the binding of transcription factors (TFs) to regulatory genomic regions. First introns are longer than other introns in multiple eukaryotic species and are under selective constraint. Here we explore the importance of first introns in TF binding in the nematode...

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Auteurs principaux: Fuxman Bass, Juan I., Tamburino, Alex M., Mori, Akihiro, Beittel, Nathan, Weirauch, Matthew T., Reece-Hoyes, John S., Walhout, Albertha J. M.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874175/
https://ncbi.nlm.nih.gov/pubmed/24068555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt858
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