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The NAD(+)-dependent Sir2p histone deacetylase is a negative regulator of chromosomal DNA replication
The establishment of DNA synthesis during the S phase is a multistep process that occurs in several stages beginning in late mitosis. The first step is the formation of a large prereplicative complex (pre-RC) at individual replication origins and occurs during exit from mitosis and entry into G1 pha...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387417/ https://ncbi.nlm.nih.gov/pubmed/15082529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1173204 |
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