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A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma brucei

SIR2-like proteins have been implicated in a wide range of cellular events including chromosome silencing, chromosome segregation, DNA recombination and the determination of life span. We report here the molecular and functional characterization of a SIR2-related protein from the protozoan parasite...

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Hlavní autoři: García-Salcedo, José A., Gijón, Purificación, Nolan, Derek P., Tebabi, Patricia, Pays, Etienne
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC275410/
https://ncbi.nlm.nih.gov/pubmed/14592982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg553
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