DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures

DNA polymerase ζ (Pol ζ) and Rev1 are key players in translesion DNA synthesis. The error-prone Pol ζ can also participate in replication of undamaged DNA when the normal replisome is impaired. Here we define the nature of the replication disturbances that trigger the recruitment of error-prone poly...

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Bibliographische Detailangaben
Hauptverfasser: Northam, Matthew R., Moore, Elizabeth A., Mertz, Tony M., Binz, Sara K., Stith, Carrie M., Stepchenkova, Elena I., Wendt, Kathern L., Burgers, Peter M. J., Shcherbakova, Polina V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874155/
https://ncbi.nlm.nih.gov/pubmed/24049079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt830
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