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A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases

The delivery of site-specific post-translational modifications to histones generates an epigenetic regulatory network that directs fundamental DNA-mediated processes and governs key stages in development. Methylation of histone H4 lysine-20 has been implicated in DNA repair, transcriptional silencin...

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Autors principals: Southall, Stacey M., Cronin, Nora B., Wilson, Jon R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874154/
https://ncbi.nlm.nih.gov/pubmed/24049080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt776
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