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Active, soluble recombinant melittin purified by extracting insoluble lysate of Escherichia coli without denaturation

Cell lytic peptides are a class of drugs that can be used to selectively kill invading organisms or diseased cells. Several of these peptides have been identified as potential therapeutics. Herein, we report a novel process for purifying recombinant melittin, a cell lytic peptide that inserts into t...

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Detalhes bibliográficos
Main Authors: Buhrman, Jason S., Cook, Laura C., Rayahin, Jamie E., Federle, Michael J., Gemeinhart, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874069/
https://ncbi.nlm.nih.gov/pubmed/23926061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.1784
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