β1 Integrin Signaling Maintains Human Epithelial Progenitor Cell Survival In Situ and Controls Proliferation, Apoptosis and Migration of Their Progeny

β1 integrin regulates multiple epithelial cell functions by connecting cells with the extracellular matrix (ECM). While β1 integrin-mediated signaling in murine epithelial stem cells is well-studied, its role in human adult epithelial progenitor cells (ePCs) in situ remains to be defined. Using micr...

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Detalles Bibliográficos
Main Authors: Ernst, Nancy, Yay, Arzu, Bíró, Tamás, Tiede, Stephan, Humphries, Martin, Paus, Ralf, Kloepper, Jennifer E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874009/
https://ncbi.nlm.nih.gov/pubmed/24386370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084356
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