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A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ

Cannabinoid receptors (CB) are expressed throughout human skin epithelium. CB1 activation inhibits human hair growth and decreases proliferation of epidermal keratinocytes. Since psoriasis is a chronic hyperproliferative, inflammatory skin disease, it is conceivable that the therapeutic modulation o...

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Detalhes bibliográficos
Main Authors: Ramot, Yuval, Sugawara, Koji, Zákány, Nóra, Tóth, Balázs I., Bíró, Tamás, Paus, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628749/
https://ncbi.nlm.nih.gov/pubmed/23638377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.40
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