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Processive acceleration of actin barbed-end assembly by N-WASP

Neuronal Wiskott–Aldrich syndrome protein (N-WASP)–activated actin polymerization drives extension of invadopodia and podosomes into the basement layer. In addition to activating Arp2/3, N-WASP binds actin-filament barbed ends, and both N-WASP and barbed ends are tightly clustered in these invasive...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Khanduja, Nimisha, Kuhn, Jeffrey R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873893/
https://ncbi.nlm.nih.gov/pubmed/24227886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-11-0781
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