HPV 5 and 8 E6 Expression Reduces ATM Protein Levels and Attenuates LINE-1 Retrotransposition

The expression of the E6 protein from certain members of the HPV genus β (β HPV 5 and 8 E6) can disrupt p53 signaling by diminishing the steady state levels of two p53 modifying enzymes, ATR and p300. Here, we show that β-HPV 5 and 8 E6 are also capable of reducing the steady state levels of another...

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Detaylı Bibliyografya
Asıl Yazarlar: Wallace, Nicholas A., Gasior, Stephen L., Faber, Zachary J., Howie, Heather L., Deininger, Prescott L., Galloway, Denise A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873879/
https://ncbi.nlm.nih.gov/pubmed/23706308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.04.022
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