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A common functional promoter variant links CNR1 gene expression to HDL cholesterol level

CB(1) receptor blockers increase HDL-C levels. Although genetic variation in the CB(1) receptor – encoded by the CNR1 gene – is known to influence HDL-C level as well, human studies conducted to date have been limited to genetic markers such as haplotype tagging SNPs. Here we identify rs806371 in th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Feng, Q, Vickers, KC, Anderson, MP, Levin, MG, Chen, W, Harrison, DG, Wilke, RA
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873874/
https://ncbi.nlm.nih.gov/pubmed/23748922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2973
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