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Ruthenium Catalyzed Hydrohydroxyalkylation of Acrylates with Diols and α-Hydroxycarbonyl Compounds to Form Spiro- and α-Methylene-γ-Butyrolactones

Under the conditions of ruthenium(0) catalyzed hydrohydroxyalkylation, vicinal diols 1a–1l and methyl acrylate 2a are converted to the corresponding lactones 3a–3l in good to excellent yield. The reaction of methyl acrylate 2a with hydrobenzoin 1f, benzoin didehydro-1f, and benzil tetradehydro-1f fo...

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Detalhes bibliográficos
Main Authors: McInturff, Emma L., Mowat, Jeffrey, Waldeck, Andrew R., Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873753/
https://ncbi.nlm.nih.gov/pubmed/24187991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja410533y
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