Melanoma cells transfected to express CD83 induce antitumor immunity that can be increased by also engaging CD137

Interactions between CD83 and its ligand(s) can up-regulate immune responses. M2-CD83 cells, derived by transfecting the M2 clone of mouse melanoma K1735 cells to express mouse CD83, were rejected by syngeneic mice, unless they were injected with a CD83Ig fusion protein. Rejection was mediated by CD...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Yang, Shilin, Yang, Yi, Raycraft, John, Zhang, Hongtao, Kanan, Sandra, Guo, Yajun, Ronai, Ze'ev, Hellstrom, Ingegerd, Hellstrom, Karl Erik
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2004
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15051893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400880101
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