Substrate Specificity of Purified Recombinant Human β-Carotene 15,15′-Oxygenase (BCO1)

Humans cannot synthesize vitamin A and thus must obtain it from their diet. β-Carotene 15,15′-oxygenase (BCO1) catalyzes the oxidative cleavage of provitamin A carotenoids at the central 15–15′ double bond to yield retinal (vitamin A). In this work, we quantitatively describe the substrate specifici...

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Main Authors: dela Seña, Carlo, Narayanasamy, Sureshbabu, Riedl, Kenneth M., Curley, Robert W., Schwartz, Steven J., Harrison, Earl H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2013
Ábhair:
Metabolism
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873565/
https://ncbi.nlm.nih.gov/pubmed/24187135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507160
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