Characterization of Cholesterol Homeostasis in Telomerase-immortalized Tangier Disease Fibroblasts Reveals Marked Phenotype Variability

We compared the consequences of an ABCA1 mutation that produced an apparent lack of atherosclerosis (Tangier family 1, N935S) with an ABCA1 mutation with functional ABCA1 knockout that was associated with severe atherosclerosis (Tangier family 2, Leu(548):Leu(575)-End), using primary and telomerase-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kannenberg, Frank, Gorzelniak, Kerstin, Jäger, Kathrin, Fobker, Manfred, Rust, Stephan, Repa, Joyce, Roth, Mike, Björkhem, Ingemar, Walter, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Lipids
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873552/
https://ncbi.nlm.nih.gov/pubmed/24196952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.500256
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge